Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | TOP2A | P11388 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21742301 | 0.94 | SMN1; SMN2 (0.42) | SMN1; SMN2L3MBTL1CHRM3AHRCETP | |
| SCHEMBL21742113 | 0.94 | SMN1; SMN2 (0.42) | SMN1; SMN2L3MBTL1CHRM3AHRCETP | |
| SCHEMBL21742129 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL1CHRM3AHRCHRM2 | |
| SCHEMBL21742120 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2L3MBTL1CHRM3CHRM2MAPT | |
| SCHEMBL21742388 | 0.76 | SMN1; SMN2 (0.37) | SMN1; SMN2L3MBTL1CHRM3AHRCHRM2 | |
| SCHEMBL16234253 | 0.74 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1AHRCHRM2TOP2A | |
| SCHEMBL21742028 | 0.74 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1AHRCHRM2NR1H2 | |
| SCHEMBL21742019 | 0.74 | SMN1; SMN2 (0.38) | SMN1; SMN2L3MBTL1CHRM3AHRCHRM2 | |
| SCHEMBL21742275 | 0.74 | SMN1; SMN2 (0.38) | SMN1; SMN2L3MBTL1CHRM3AHRCHRM2 | |
| SCHEMBL21742184 | 0.74 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL1CHRM3AHRCETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611164-A1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | Mitsui Chemicals Agro, Inc. (JP) | 2020-02-19 | — | — | EP | disclosed |