SCHEMBL21743221

SCHEMBL21743221

CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(CNC(=O)CCC(C)=O)cc1

nearest known ligand 0.88

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TLR7 Q9NYK1 20/20 0.88
▸ TLR8 Q9NR97 13/20 0.87

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29580352 1.00 TLR7 (0.88) TLR7TLR8
SCHEMBL24368861 0.96 TLR7 (0.93) TLR7TLR8
SCHEMBL24757414 0.95 TLR7 (0.95) TLR7TLR8
SCHEMBL20766799 0.94 TLR7 (0.96) TLR7TLR8
SCHEMBL29381770 0.94 TLR7 (0.96) TLR7TLR8
SCHEMBL13968059 0.94 TLR7 (1.00) TLR7TLR8
SCHEMBL20983639 0.93 TLR7 (1.00) TLR7TLR8
SCHEMBL16019254 0.93 TLR7 (1.00) TLR7TLR8
SCHEMBL16019253 0.93 TLR7 (1.00) TLR7TLR8
SCHEMBL29382380 0.93 TLR7 (1.00) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022086853-A1 STAR POLYMER DRUG CONJUGATES AVIDEA TECHNOLOGIES, INC. (US) 2022-04-28 — — WO disclosed
US-20200054741-A1 PEPTIDE-BASED VACCINES, METHODS OF MANUFACTURING, AND USES THEREOF FOR INDUCING AN IMMUNE RESPONSE AVIDEA TECHNOLOGIES, INC. (US) 2020-02-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200054741-A1 PEPTIDE-BASED VACCINES, METHODS OF MANUFACTURING, AND USES THEREOF FOR INDUCING AN IMMUNE RESPONSE MYD88, ICOS, CD4 TLR7 71/4885TLR8 113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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