Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CCR1 | P32246 | 3/20 | 0.34 |
| ▸ | CCR5 | P51681 | 3/20 | 0.34 |
| ▸ | CCR8 | P51685 | 3/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | GPR39 | O43194 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25887036 | 0.92 | HIF1A (0.34) | HSP90AA1L3MBTL1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL21861168 | 0.91 | MCL1 (0.40) | HSP90AA1CCR1CCR5CCR8SLC2A1 | |
| SCHEMBL24762515 | 0.90 | CNR2 (0.32) | HSP90AA1MCL1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL19313649 | 0.89 | TRPV1 (0.33) | HSP90AA1L3MBTL1CCR1CCR5CCR8 | |
| SCHEMBL23176879 | 0.86 | SIRT2 (0.36) | HSP90AA1CYP2C9KDM4ELMNASMN1; SMN2 | |
| SCHEMBL23764098 | 0.81 | — | — | |
| SCHEMBL21935789 | 0.81 | MAPK1 (0.30) | RAB9AMAPK1 | |
| SCHEMBL20169567 | 0.80 | KAT6A (0.35) | HSP90AA1L3MBTL1CCR1CCR5CCR8 | |
| SCHEMBL24609840 | 0.79 | CYP2C9 (0.32) | CYP2C9LMNA | |
| SCHEMBL21308670 | 0.78 | CYP2C9 (0.31) | HSP90AA1ADORA3CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200054647-A1 | RUTHENIUM COMPLEXES FOR TREATING CANCER WHICH COMPRISES CANCER STEM CELLS | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200054647-A1 | RUTHENIUM COMPLEXES FOR TREATING CANCER WHICH COMPRISES CANCER STEM CELLS | MYC, MYCBP, MCL1 | HSP90AA1 2364/4885L3MBTL1 1053/4885CCR1 3259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.