SCHEMBL21743604

SCHEMBL21743604

c1ccc(-c2cc(-c3ccccc3)nc(-c3ccc(-c4ccc5c(c4)C(c4ccccc4)(c4ccccc4)c4ccccc4S5)cc3)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.38
MEN1 O00255 7/20 0.38
KMT2A Q03164 7/20 0.38
MAPT P10636 4/20 0.35
KDM4E B2RXH2 3/20 0.35
MCL1 Q07820 2/20 0.35
MYC P01106 1/20 0.34
CTRC Q99895 1/20 0.34
PDK2 Q15119 1/20 0.34
ADORA1 P30542 2/20 0.33
ADORA3 P0DMS8 1/20 0.33
ADORA2B P29275 1/20 0.33
DRD2 P14416 1/20 0.33
ALDH1A1 P00352 4/20 0.33
HPGD P15428 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
RAB9A P51151 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
NTSR1 P30989 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21743603 0.97 CYP19A1 (0.38) CYP19A1MEN1KMT2AMAPTKDM4E
SCHEMBL21743580 0.96 CYP19A1 (0.35) CYP19A1MEN1KMT2AMAPTKDM4E
SCHEMBL21743599 0.96 CYP19A1 (0.35) CYP19A1MEN1KMT2AMAPTKDM4E
SCHEMBL21743598 0.93 CYP19A1 (0.37) CYP19A1MEN1KMT2AMAPTKDM4E
SCHEMBL21743605 0.91 CYP19A1 (0.37) CYP19A1MEN1KMT2AMAPTKDM4E
SCHEMBL21743399 0.91 MEN1 (0.44) MEN1KMT2AMAPTKDM4ECTRC
SCHEMBL21743608 0.90 CYP19A1 (0.35) CYP19A1MEN1KMT2AMAPTKDM4E
SCHEMBL21743602 0.90 CYP19A1 (0.35) CYP19A1MEN1KMT2AMAPTKDM4E
SCHEMBL21743631 0.88 MEN1 (0.40) MEN1KMT2AMAPTKDM4EPDK2
SCHEMBL21743382 0.88 MEN1 (0.43) MEN1KMT2AMAPTKDM4EADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020036313-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-02-20 WO disclosed