Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 8/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.43 |
| ▸ | CD44 | P16070 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21743768 | 0.92 | CXCR4 (0.48) | CXCR4CYP2C9TIPARPCYP2D6CD44 | |
| SCHEMBL30101383 | 0.88 | CXCR4 (0.48) | CXCR4CYP2C9TIPARPCYP2D6CHRM3 | |
| SCHEMBL21744605 | 0.85 | CD44 (0.46) | CXCR4CD44CHRM3CHRM2CHRM1 | |
| SCHEMBL28183367 | 0.85 | CXCR4 (0.41) | CXCR4CYP2C9TIPARPCYP2D6CD44 | |
| SCHEMBL21744165 | 0.82 | CD44 (0.46) | CXCR4CYP2C9CYP2D6CD44CHRM3 | |
| SCHEMBL21744248 | 0.82 | CD44 (0.50) | CXCR4TIPARPCYP2D6CD44CHRM3 | |
| SCHEMBL16110838 | 0.82 | CD44 (0.43) | CXCR4CYP2D6CD44CHRM3CHRM2 | |
| SCHEMBL16485203 | 0.80 | CD44 (0.50) | CD44TLR9TLR7HTR2C | |
| SCHEMBL30101385 | 0.80 | CXCR4 (0.48) | CXCR4CYP2C9TIPARPCYP2D6CHRM3 | |
| SCHEMBL21744394 | 0.80 | HTR2C (0.54) | CYP2D6CD44HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230112832-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | UNIV EMORY (US) | 2023-04-13 | — | — | US | disclosed |
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | EMORY UNIVERSITY | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | CXCR4 1/4885CYP2C9 4817/4885TIPARP 2290/4885 |
| US-20230112832-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | CXCR4 1/4885CYP2C9 4817/4885TIPARP 2290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.