SCHEMBL2174381

SCHEMBL2174381

CC(C)(C)N(CCCCCCCCCCCCN)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.41
LMNA P02545 3/20 0.40
THRB P10828 2/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
PLG P00747 1/20 0.40
ALOX15 P16050 1/20 0.40
SLC6A2 P23975 1/20 0.40
RECQL P46063 1/20 0.40
SLC6A3 Q01959 1/20 0.40
PAOX Q6QHF9 3/20 0.39
CYP2D6 P10635 1/20 0.37
NFKB1 P19838 1/20 0.37
CPB2 Q96IY4 4/20 0.36
BLM P54132 3/20 0.35
NPSR1 Q6W5P4 2/20 0.35
TSHR P16473 2/20 0.33
GABRR3 A8MPY1 1/20 0.33
GABRP O00591 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2121005 1.00 CHRM2 (0.41) CHRM2LMNATHRBKMT2AMEN1
SCHEMBL146038 1.00 CHRM2 (0.41) CHRM2LMNATHRBKMT2AMEN1
SCHEMBL27220640 1.00 CHRM2 (0.41) CHRM2LMNATHRBKMT2AMEN1
SCHEMBL2125590 1.00 CHRM2 (0.41) CHRM2LMNATHRBKMT2AMEN1
Hydrochloric Acid SCHEMBL6157108 0.98 CHRM2 (0.40) CHRM2LMNATHRBKMT2AMEN1
SCHEMBL838138 0.98 CHRM2 (0.38) CHRM2LMNATHRBKMT2AMEN1
Ammonia Solution, Strong SCHEMBL22716834 0.96 CHRM2 (0.37) CHRM2LMNATHRBKMT2AMEN1
SCHEMBL838329 0.92 KMT2A (0.36) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL22321638 0.84 MEN1 (0.31) KMT2AMEN1
SCHEMBL5452674 0.83 CHRM2 (0.42) CHRM2LMNATHRBKMT2ABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023212650-A1 NEXT GENERATION DIPROVOCIMS THAT ACTIVATE THE INNATE AND ADAPTIVE IMMUNE RESPONSE THE SCRIPPS RESEARCH INSTITUTE (US) 2023-11-02 WO disclosed
US-9707294-B2 Transfection with magnetic nanoparticles HIDACA LIMITED (CA) 2017-07-18 US disclosed
US-9339539-B2 Transfection with magnetic nanoparticles HIDACA LIMITED (CA) 2016-05-17 US disclosed
US-20150344869-A1 TRANSFECTION WITH MAGNETIC NANOPARTICLES INTELLENGENTNANO INC (CA) 2015-12-03 US disclosed
US-20120214218-A1 TRANSFECTION WITH MAGNETIC NANOPARTICLES AND ULTRASOUND INTELLIGENTNANO INC. (CA) 2012-08-23 US disclosed
CN-102272312-A Transfection with magnetic nanoparticles and ultrasound 2011-12-07 CN disclosed
US-20110251547-A1 TRANSFECTION WITH MAGNETIC NANOPARTICLES AND ULTRASOUND INTELLIGENTNANO INC. (CA) 2011-10-13 US disclosed
EP-2346996-A1 TRANSFECTION WITH MAGNETIC NANOPARTICLES AND ULTRASOUND Intelligentnano Inc. (CA) 2011-07-27 EP disclosed
WO-2010051643-A1 TRANSFECTION WITH MAGNETIC NANOPARTICLES AND ULTRASOUND INTELLIGENTNANO INC. (CA) 2010-05-14 WO disclosed