Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 20/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 9/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.86 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.86 |
| ▸ | CHRM5 | P08912 | 7/20 | 0.86 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.86 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.86 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21744237 | 1.00 | CXCR4 (1.00) | CXCR4CYP2D6CYP3A4CHRM2CHRM4 | |
| SCHEMBL21744412 | 1.00 | CXCR4 (1.00) | CXCR4CYP2D6CYP3A4CHRM2CHRM4 | |
| SCHEMBL21744281 | 0.94 | CXCR4 (1.00) | CXCR4CYP2D6CYP3A4CHRM2CHRM4 | |
| SCHEMBL21744415 | 0.94 | CXCR4 (1.00) | CXCR4CYP2D6CYP3A4CHRM2CHRM4 | |
| SCHEMBL21744235 | 0.93 | CXCR4 (1.00) | CXCR4CYP2D6CYP3A4CHRM2CHRM4 | |
| SCHEMBL21744749 | 0.93 | CXCR4 (1.00) | CXCR4CYP2D6CYP3A4CHRM2CHRM4 | |
| SCHEMBL21744236 | 0.93 | CXCR4 (1.00) | CXCR4CYP2D6CYP3A4CHRM2CHRM4 | |
| SCHEMBL21744363 | 0.92 | CXCR4 (1.00) | CXCR4CYP2D6CYP3A4CHRM2CHRM4 | |
| SCHEMBL21744364 | 0.92 | CXCR4 (1.00) | CXCR4CYP2D6CYP3A4CHRM2CHRM4 | |
| SCHEMBL21744240 | 0.91 | CXCR4 (1.00) | CXCR4CYP2D6CYP3A4CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230112832-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | UNIV EMORY (US) | 2023-04-13 | — | — | US | disclosed |
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | EMORY UNIVERSITY | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | CXCR4 1/4885CYP2D6 4404/4885CYP3A4 4527/4885 |
| US-20230112832-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | CXCR4 1/4885CYP2D6 4404/4885CYP3A4 4527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.