SCHEMBL2174440

SCHEMBL2174440

C1=Cc2cccc3c2N(C1)CC3

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 4/20 0.43
ACHE P22303 1/20 0.39
MAPT P10636 4/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
ALDH1A1 P00352 2/20 0.35
CYP1A2 P05177 2/20 0.35
HSD17B10 Q99714 2/20 0.35
HTR1A P08908 2/20 0.35
KDM4E B2RXH2 2/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
CES1 P23141 2/20 0.34
HTR2B P41595 2/20 0.33
NOTUM Q6P988 1/20 0.33
GRIN2D O15399 3/20 0.33
GRIN3B O60391 3/20 0.33
GRIN1 Q05586 3/20 0.33
GRIN2A Q12879 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3333311 0.89 HTR2C (0.46) HTR2CACHEMEN1KMT2AALDH1A1
SCHEMBL6228672 0.77
SCHEMBL11566174 0.74 HTR2C (0.41) HTR2CHTR1ACES1HTR2B
SCHEMBL10153320 0.74 HTR2C (0.67) HTR2CACHEMAPTMEN1KMT2A
SCHEMBL9827238 0.73
SCHEMBL2084830 0.72 HTR2C (0.47) HTR2CACHEMEN1KMT2AALDH1A1
SCHEMBL35212134 0.69 HTR2C (0.30) HTR2C
SCHEMBL28730888 0.67 NOTUM (0.33) ACHENOTUM
SCHEMBL2338214 0.67 HTR2C (0.65) HTR2CACHEMAPTMEN1KMT2A
SCHEMBL4509562 0.67 CA1 (0.31) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0000599-B1 ELECTRICALLY PHOTOSENSITIVE PARTICLES FOR PHOTOELECTROPHORETIC MIGRATION IMAGING PROCESSES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-02-02 EP claimed
US-4293626-A ORGANIC PIGMENT EASTMAN KODAK COMPANY (US) 1981-10-06 US claimed
US-4272595-A UNSATURATED NITRILE EASTMAN KODAK COMPANY (US) 1981-06-09 US claimed
US-4254198-A Electrophotosensitive materials for migration imaging processes EASTMAN KODAK COMPANY (US) 1981-03-03 US claimed
US-4251609-A Isoquinolinedione photoelectrophoretic materials for imaging processes EASTMAN KODAK COMPANY (US) 1981-02-17 US claimed
US-4241157-A ORGANIC PIGMENTS CONTAINING PYRIMIDINE RING EASTMAN KODAK COMPANY (US) 1980-12-23 US claimed
EP-0005652-A2 Electrophoretic migration imaging process and dispersion EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-11-28 EP claimed
US-4166740-A CYANINE DYES EASTMAN KODAK COMPANY (US) 1979-09-04 US claimed
US-4165985-A PHOTOCONDUCTIVE, HETEROCYCLIC-SUBSTITUTED ISOQUINOLINE COLORANTS EASTMAN KODAK COMPANY (US) 1979-08-28 US claimed
US-4145215-A PHOTOCONDUCTIVE PIGMENTS EASTMAN KODAK COMPANY (US) 1979-03-20 US claimed
EP-0000596-A1 Electrically photosensitive particles for electrophoretic migration imaging processes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-02-07 EP claimed
EP-0000599-A1 Electrically photosensitive particles for photoelectrophoretic migration imaging processes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-02-07 EP claimed
WO-2011082266-A2 SUBSTITUTED HETEROCYCLIC COMPOUNDS ARQULE, INC. (US) 2011-07-07 WO disclosed
US-7772227-B2 Tricyclic 1-[(indol-3-yl)carbonyl]piperazine derivatives as cannabinoid CB1 receptor agonists N.V. ORGANON (NL) 2010-08-10 US disclosed
US-7700634-B2 (Indol-3-yl) heterocycle derivatives as agonists of the cannabinoid CB1 receptor N.V. ORGANON (NL) 2010-04-20 US disclosed
EP-1725232-B1 (INDOL-3-YL)-HETEROCYCLE DERIVATIVES AS AGONISTS OF THE CANNABINOID CB1 RECEPTOR ORGANON NV (NL) 2008-01-23 EP disclosed
US-4165985-A PHOTOCONDUCTIVE, HETEROCYCLIC-SUBSTITUTED ISOQUINOLINE COLORANTS EASTMAN KODAK COMPANY (US) 1979-08-28 US disclosed
US-4145215-A PHOTOCONDUCTIVE PIGMENTS EASTMAN KODAK COMPANY (US) 1979-03-20 US disclosed
EP-0000599-A1 Electrically photosensitive particles for photoelectrophoretic migration imaging processes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-02-07 EP disclosed
EP-0000596-A1 Electrically photosensitive particles for electrophoretic migration imaging processes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-02-07 EP disclosed