Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | RB1 | P06400 | 2/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882174 | 0.93 | HDAC1 (0.49) | HDAC1HDAC6ADORA2ACXCR4SCN1A | |
| SCHEMBL18157989 | 0.85 | HDAC1 (0.52) | HDAC1HDAC6ADORA2ACXCR4SCN1A | |
| SCHEMBL14130906 | 0.85 | HDAC1 (0.44) | HDAC1HDAC6CXCR4 | |
| SCHEMBL30096647 | 0.82 | HDAC1 (0.49) | HDAC1HDAC6ADORA2AP2RX7MAPK1 | |
| SCHEMBL3081802 | 0.79 | HDAC1 (0.50) | HDAC1HDAC6ADORA2ACXCR4SCN1A | |
| SCHEMBL4891510 | 0.79 | HDAC1 (0.50) | HDAC1HDAC6ADORA2ACXCR4SCN1A | |
| SCHEMBL3088474 | 0.79 | HDAC1 (0.50) | HDAC1HDAC6ADORA2ACXCR4SCN1A | |
| SCHEMBL4710642 | 0.78 | CXCR4 (0.46) | HDAC1HDAC6CXCR4CYP2D6 | |
| SCHEMBL5059176 | 0.78 | CXCR4 (0.46) | HDAC1HDAC6CXCR4CYP2D6 | |
| SCHEMBL5057601 | 0.78 | CXCR4 (0.46) | HDAC1HDAC6CXCR4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | EMORY UNIVERSITY | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | HDAC1 1180/4885HDAC6 1205/4885ADORA2A 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.