Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21746970 | 0.88 | KLKB1 (0.51) | KLKB1 | |
| SCHEMBL21746520 | 0.84 | KLKB1 (0.56) | KLKB1 | |
| SCHEMBL21736677 | 0.84 | KLKB1 (0.61) | KLKB1 | |
| SCHEMBL31741492 | 0.84 | KLKB1 (0.61) | KLKB1 | |
| SCHEMBL31741463 | 0.80 | KLKB1 (0.58) | KLKB1 | |
| SCHEMBL21736672 | 0.80 | KLKB1 (0.58) | KLKB1 | |
| SCHEMBL30140714 | 0.80 | KLKB1 (0.45) | KLKB1 | |
| SCHEMBL21713053 | 0.80 | KLKB1 (0.45) | KLKB1 | |
| SCHEMBL21746964 | 0.75 | KLKB1 (0.48) | KLKB1 | |
| SCHEMBL21736676 | 0.74 | KLKB1 (0.60) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035540-A1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-02-20 | — | — | WO | disclosed |