Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31033224 | 1.00 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL21712995 | 1.00 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL21736907 | 0.93 | KLKB1 (0.79) | KLKB1 | |
| SCHEMBL21736693 | 0.90 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL21736691 | 0.89 | KLKB1 (0.81) | KLKB1 | |
| SCHEMBL21736687 | 0.89 | KLKB1 (0.81) | KLKB1 | |
| SCHEMBL21736754 | 0.86 | KLKB1 (0.63) | KLKB1 | |
| SCHEMBL21712935 | 0.85 | KLKB1 (0.70) | KLKB1 | |
| SCHEMBL21712943 | 0.85 | KLKB1 (0.79) | KLKB1 | |
| SCHEMBL21712939 | 0.85 | KLKB1 (0.79) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035540-A1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-02-20 | — | — | WO | disclosed |