Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL897745 | 0.95 | ALK (0.54) | ALK | |
| SCHEMBL897843 | 0.87 | ALK (0.57) | ALK | |
| SCHEMBL897782 | 0.87 | ALK (0.69) | ALK | |
| SCHEMBL897013 | 0.86 | ALK (0.58) | ALK | |
| SCHEMBL897675 | 0.82 | ALK (0.58) | ALK | |
| SCHEMBL17434715 | 0.80 | ALK (0.57) | ALK | |
| SCHEMBL897676 | 0.80 | ALK (0.54) | ALK | |
| SCHEMBL897743 | 0.77 | ALK (0.60) | ALK | |
| SCHEMBL897742 | 0.77 | ALK (0.60) | ALK | |
| SCHEMBL16775644 | 0.77 | ALK (0.60) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613729-A1 | TETRACYCLIC COMPOUNDS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2020-02-26 | — | — | EP | disclosed |