Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21747653 | 0.86 | CACNA2D1 (0.57) | CACNA2D1SLC6A2 | |
| SCHEMBL21747673 | 0.85 | CACNA2D1 (0.69) | CACNA2D1SLC6A2 | |
| SCHEMBL21747660 | 0.83 | CACNA2D1 (0.56) | CACNA2D1SLC6A2 | |
| SCHEMBL19552904 | 0.83 | CACNA2D1 (0.52) | CACNA2D1SLC6A2 | |
| SCHEMBL21747689 | 0.81 | CACNA2D1 (0.59) | CACNA2D1SLC6A2 | |
| SCHEMBL21747652 | 0.79 | CACNA2D1 (0.58) | CACNA2D1SLC6A2 | |
| SCHEMBL21770954 | 0.78 | CACNA2D1 (0.65) | CACNA2D1SLC6A2 | |
| SCHEMBL21747654 | 0.78 | CACNA2D1 (0.57) | CACNA2D1SLC6A2 | |
| SCHEMBL21747666 | 0.77 | CACNA2D1 (0.55) | CACNA2D1SLC6A2 | |
| SCHEMBL21747679 | 0.76 | CACNA2D1 (0.54) | CACNA2D1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452475-B1 | TETRAHYDROPYRIMIDODIAZEPINE AND TETRAHYDROPYRIDODIAZEPINE COMPOUNDS FOR TREATING PAIN AND PAIN RELATED CONDITIONS | ESTEVE PHARMACEUTICALS SA (ES) | 2020-02-26 | — | — | EP | claimed |