SCHEMBL2174805

SCHEMBL2174805

COCOCCc1ccc(Cc2cc(C3(O)O[C@H](COCc4ccccc4)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)ccc2Cl)cc1

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 8/20 0.34
MCHR1 Q99705 2/20 0.32
PTPN1 P18031 6/20 0.32
CDC25B P30305 6/20 0.32
SSTR5 P35346 2/20 0.31
SSTR1 P30872 1/20 0.31
SSTR2 P30874 1/20 0.31
SSTR4 P31391 1/20 0.31
SSTR3 P32745 1/20 0.31
SLC5A1 P13866 2/20 0.31
PTPN2 P17706 2/20 0.30
PTPN6 P29350 2/20 0.30
PTPN11 Q06124 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2174811 1.00 SLC5A2 (0.34) SLC5A2MCHR1PTPN1CDC25BSSTR5
SCHEMBL12407964 0.88 SLC5A2 (0.36) SLC5A2MCHR1SLC5A1
SCHEMBL2176303 0.86 SLC5A2 (0.32) SLC5A2MCHR1PTPN1CDC25B
SCHEMBL2176298 0.86 SLC5A2 (0.32) SLC5A2MCHR1PTPN1CDC25B
SCHEMBL1035412 0.85 SLC5A2 (0.50) SLC5A2SLC5A1
SCHEMBL29940875 0.85 SLC5A2 (0.50) SLC5A2SLC5A1
SCHEMBL499751 0.84 SLC5A2 (0.40) SLC5A2PTPN1CDC25BSLC5A1PTPN2
SCHEMBL20139485 0.82 SLC5A2 (0.40) SLC5A2PTPN1SLC5A1PTPN2PTPN11
SCHEMBL499844 0.80 SLC5A2 (0.37) SLC5A2SSTR5SSTR1SSTR2SSTR4
SCHEMBL1457373 0.80 PTPN1 (0.37) SLC5A2PTPN1CDC25BSSTR5SSTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2076503-B1 C-PHENYL GLYCITOL COMPOUND FOR THE TREATMENT OF DIABETES TAISHO PHARMACEUTICAL CO LTD (JP) 2013-07-17 EP disclosed
US-7973012-B2 C-phenyl glycitol compound TAISHO PHARMACEUTICAL CO., LTD (JP) 2011-07-05 US disclosed
US-20100022460-A1 C-PHENYL GLYCITOL COMPOUND TAISHO PHARMACEUTICAL CO., LTD. (JP) 2010-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100022460-A1 C-PHENYL GLYCITOL COMPOUND SLC5A1, SLC5A2, SLC2A1 SLC5A2 2/4885MCHR1 1232/4885PTPN1 1941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.