SCHEMBL2174822

SCHEMBL2174822

PSS

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trisulfane SCHEMBL36954 0.61
Trisulfane SCHEMBL737023 0.61
SCHEMBL19857298 0.61
SCHEMBL3136986 0.55
SCHEMBL36955 0.55
SCHEMBL1132412 0.50
SCHEMBL17137757 0.50
SCHEMBL11530096 0.50
SCHEMBL4178651 0.50
SCHEMBL9820888 0.50

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118139880-A O-linked N-acetylglucosamine hydrolase (OGA) inhibitor combination therapy 伊莱利利公司 2024-06-04 CN disclosed
EP-3567040-B1 METHOD FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR THE SYNTHESIS OF [1,2,4]-TRIAZOLO[4,3-A]PYRIDINES AMGEN INC (US) 2020-09-09 EP disclosed
WO-2020152200-A1 PROCESS FOR PREPARATION OF HETEROARYLKETONES BASF SE (DE) 2020-07-30 WO disclosed
EP-3567040-A1 METHOD FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR THE SYNTHESIS OF [1,2,4]-TRIAZOLO[4,3-A]PYRIDINES Amgen, Inc (US) 2019-11-13 EP disclosed
EP-3013825-B1 METHOD FOR THE PREPARATION OF (1,2,4)-TRIAZOLO(4,3-A)PYRIDINES AMGEN INC (US) 2019-08-07 EP disclosed
US-9707553-B2 P-chirogenic organophosphorus compounds CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2017-07-18 US disclosed
US-9643984-B2 Method for the preparation of [1,2,4]-triazolo[4,3-a]pyridines AMGEN INC. (US) 2017-05-09 US disclosed
EP-3150613-A1 P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2017-04-05 EP disclosed
US-20160347769-A1 METHOD FOR THE PREPARATION OF [1,2,4]-TRIAZOLO[4,3-A]PYRIDINES AMGEN INC. 2016-12-01 US disclosed
EP-2731956-B1 P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS CENTRE NAT RECH SCIENT (FR) 2016-11-09 EP disclosed
CN-1867331-A Thalidomide analogs as TNF-alpha modulators US GOV HEALTH & HUMAN SERV (US) 2006-11-22 CN disclosed
US-20060211728-A1 Thalidomide analogs P2D INC. 2006-09-21 US disclosed
EP-1663223-A2 THALIDOMIDE ANALOGS AS TNF-ALPHA MODULATORS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE DEPARTMENT OF HEALTH &amp; HUMAN SERVICES (US) 2006-06-07 EP disclosed
WO-2005028436-A2 THALIDOMIDE ANALOGS AS TNF-ALPHA MODULATORS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2005-03-31 WO disclosed
EP-1272574-B1 INDIVIDUAL INKS AND AN INK SET FOR USE IN THE COLOR INK JET PRINTING OF GLAZED CERAMIC TILES AND SURFACES FERRO CORP (US) 2005-03-09 EP disclosed
EP-1272574-A4 INDIVIDUAL INKS AND AN INK SET FOR USE IN THE COLOR INK JET PRINTING OF GLAZED CERAMIC TILES AND SURFACES FERRO CORP (US) 2003-02-26 EP disclosed
EP-1272574-A1 INDIVIDUAL INKS AND AN INK SET FOR USE IN THE COLOR INK JET PRINTING OF GLAZED CERAMIC TILES AND SURFACES FERRO CORPORATION (US) 2003-01-08 EP disclosed
US-6402823-B1 SOLUBLE TRANSITION METAL COMPLEX FERRO CORPORATION 2002-06-11 US disclosed
WO-2001051573-A1 INDIVIDUAL INKS AND AN INK SET FOR USE IN THE COLOR INK JET PRINTING OF GLAZED CERAMIC TILES AND SURFACES FERRO CORPORATION (US) 2001-07-19 WO disclosed
US-4997950-A Antisecretory MURPHY RICHARD FINBAR (US) 1991-03-05 US disclosed