Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 9/20 | 0.51 |
| ▸ | KLK1 | P06870 | 3/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | CTRL | P40313 | 1/20 | 0.40 |
| ▸ | CTRB2 | Q6GPI1 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16068814 | 0.91 | F2 (0.62) | F2KLKB1KLK1F11CTRB1 | |
| SCHEMBL21748324 | 0.90 | F2 (0.54) | F2KLKB1KLK1F10F11 | |
| SCHEMBL21748347 | 0.89 | F2 (0.57) | F2KLKB1KLK1F10 | |
| SCHEMBL20506155 | 0.88 | F2 (0.64) | F2KLKB1KLK1F10F11 | |
| SCHEMBL21748367 | 0.86 | KLKB1 (0.50) | F2KLKB1KLK1F10 | |
| SCHEMBL21748356 | 0.82 | F2 (0.69) | F2KLKB1KLK1F10F11 | |
| SCHEMBL21748368 | 0.79 | KLKB1 (0.52) | F2KLKB1KLK1F10 | |
| SCHEMBL21748344 | 0.78 | F2 (0.60) | F2KLKB1KLK1F10F11 | |
| SCHEMBL21748323 | 0.78 | F2 (0.84) | F2KLKB1KLK1 | |
| SCHEMBL20506142 | 0.78 | KLKB1 (0.65) | F2KLKB1KLK1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970141-B1 | HALOGENOPYRAZOLES AS INHIBITORS OF THROMBIN | VERSEON CORP (US) | 2020-02-26 | — | — | EP | claimed |
| EP-2970141-B1 | HALOGENOPYRAZOLES AS INHIBITORS OF THROMBIN | VERSEON CORP (US) | 2020-02-26 | — | — | EP | disclosed |