Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 14/20 | 0.83 |
| ▸ | F2 | P00734 | 10/20 | 0.70 |
| ▸ | KLK1 | P06870 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20506168 | 0.91 | KLKB1 (1.00) | KLKB1F2KLK1 | |
| SCHEMBL20506460 | 0.82 | F2 (1.00) | KLKB1F2 | |
| SCHEMBL21748375 | 0.80 | F2 (1.00) | KLKB1F2KLK1 | |
| Hydrochloric Acid SCHEMBL18040015 | 0.80 | F2 (0.68) | KLKB1F2KLK1 | |
| SCHEMBL20506217 | 0.80 | F2 (1.00) | KLKB1F2 | |
| SCHEMBL21748323 | 0.80 | F2 (0.84) | KLKB1F2KLK1 | |
| SCHEMBL21748321 | 0.79 | F2 (0.71) | KLKB1F2KLK1 | |
| SCHEMBL21748335 | 0.79 | KLKB1 (0.79) | KLKB1F2KLK1 | |
| SCHEMBL21748345 | 0.78 | F2 (0.83) | KLKB1F2 | |
| SCHEMBL21748373 | 0.78 | F2 (0.71) | KLKB1F2KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970141-B1 | HALOGENOPYRAZOLES AS INHIBITORS OF THROMBIN | VERSEON CORP (US) | 2020-02-26 | — | — | EP | claimed |