Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 10/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ACE | P12821 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.55 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825215 | 1.00 | CMA1 (0.63) | CMA1MAPK1ACEKMT2ACTRB1 | |
| SCHEMBL3165688 | 1.00 | CMA1 (0.63) | CMA1MAPK1ACEKMT2ACTRB1 | |
| SCHEMBL3165695 | 1.00 | CMA1 (0.63) | CMA1MAPK1ACEKMT2ACTRB1 | |
| SCHEMBL30152222 | 0.96 | CMA1 (0.59) | CMA1MAPK1ACEKMT2ACTRB1 | |
| SCHEMBL30689130 | 0.92 | CMA1 (0.58) | CMA1MAPK1ACEKMT2ACTRB1 | |
| SCHEMBL28067688 | 0.92 | ACE (0.56) | CMA1ACEKMT2ACTRB1KLK5 | |
| SCHEMBL28067687 | 0.92 | ACE (0.56) | CMA1ACEKMT2ACTRB1KLK5 | |
| SCHEMBL5689963 | 0.91 | CMA1 (0.54) | CMA1MAPK1ACEKMT2AALDH1A1 | |
| SCHEMBL30487494 | 0.90 | CMA1 (0.54) | CMA1MAPK1ACEKMT2AALDH1A1 | |
| SCHEMBL5689518 | 0.89 | CMA1 (0.53) | CMA1MAPK1ACEKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817109-B1 | MIXED-MODAL ANION-EXCHANGE TYPE SEPARATION MATERIAL | MERCK PATENT GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |