⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19047109 | 0.73 | MAP3K14 (0.60) | — | |
| SCHEMBL9256 | 0.71 | — | — | |
| SCHEMBL1359359 | 0.69 | — | — | |
| Ammonia Solution, Strong SCHEMBL23360905 | 0.69 | — | — | |
| SCHEMBL908288 | 0.69 | — | — | |
| SCHEMBL1079678 | 0.69 | — | — | |
| SCHEMBL10909993 | 0.69 | — | — | |
| SCHEMBL6042160 | 0.69 | — | — | |
| Bromide SCHEMBL1086848 | 0.67 | CRBN (0.50) | — | |
| Hydrochloric Acid SCHEMBL2278643 | 0.67 | CRBN (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070155967-A1 | Process for producing piperidine-2,6 diones heterocyclically substituted in the 3-position | GRUENENTHAL GMBH (DE) | 2007-07-05 | — | — | US | claimed |
| US-20250382285-A1 | BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS | C4 THERAPEUTICS, INC. (US) | 2025-12-18 | — | — | US | disclosed |
| US-20250368631-A1 | BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS | C4 THERAPEUTICS, INC. (US) | 2025-12-04 | — | — | US | disclosed |
| US-12421220-B2 | Bicyclic-substituted glutarimide cereblon binders | C4 THERAPEUTICS, INC. (US) | 2025-09-23 | — | — | US | disclosed |
| US-20250122179-A1 | BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS | C4 THERAPEUTICS, INC. (US) | 2025-04-17 | — | — | US | disclosed |
| EP-4536656-A1 | BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS | C4 Therapeutics, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| CN-119823124-A | Compounds for targeted degradation of BRD9 | C4医药公司 | 2025-04-15 | — | — | CN | disclosed |
| US-20250084081-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 | C4 THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | US | disclosed |
| CN-115279370-B | Compounds for targeted degradation of BRD9 | C4医药公司 | 2025-01-10 | — | — | CN | disclosed |
| US-12157735-B2 | Compounds for targeted degradation of BRD9 | C4 THERAPEUTICS, INC. (US) | 2024-12-03 | — | — | US | disclosed |
| US-20060211728-A1 | Thalidomide analogs | P2D INC. | 2006-09-21 | — | — | US | disclosed |
| EP-1663223-A2 | THALIDOMIDE ANALOGS AS TNF-ALPHA MODULATORS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 2006-06-07 | — | — | EP | disclosed |
| US-20050192313-A1 | Substituted thioacetamides | CEPHALON, INC. (US) | 2005-09-01 | — | — | US | disclosed |
| US-6919367-B2 | Substituted thioacetamides | CEPHALON, INC. (US) | 2005-07-19 | — | — | US | disclosed |
| WO-2005028436-A2 | THALIDOMIDE ANALOGS AS TNF-ALPHA MODULATORS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2005-03-31 | — | — | WO | disclosed |
| EP-1438288-A1 | SUBSTITUTED THIOACETAMIDES | CEPHALON, INC. (US) | 2004-07-21 | — | — | EP | disclosed |
| US-20040116445-A1 | Substituted thioacetamides | CEPHALON INC. | 2004-06-17 | — | — | US | disclosed |
| US-6670358-B2 | Substituted thioacetamides | CEPHALON, INC. | 2003-12-30 | — | — | US | disclosed |
| WO-2003037853-A1 | SUBSTITUTED THIOACETAMIDES | CEPHALON, INC. (US) | 2003-05-08 | — | — | WO | disclosed |
| US-20020183334-A1 | Substituted thioacetamides | CEPHALON, INC. | 2002-12-05 | — | — | US | disclosed |