Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 20/20 | 0.85 |
| ▸ | AKT2 | P31751 | 11/20 | 0.83 |
| ▸ | AKT3 | Q9Y243 | 6/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802345 | 1.00 | AKT1 (0.85) | AKT1AKT2AKT3 | |
| SCHEMBL2174634 | 0.92 | AKT1 (1.00) | AKT1AKT2AKT3 | |
| SCHEMBL2176420 | 0.91 | AKT1 (1.00) | AKT1AKT2AKT3 | |
| SCHEMBL2173843 | 0.90 | AKT1 (1.00) | AKT1AKT2AKT3 | |
| SCHEMBL2192829 | 0.90 | AKT1 (1.00) | AKT1AKT2AKT3 | |
| SCHEMBL12491111 | 0.90 | AKT1 (0.88) | AKT1AKT2AKT3 | |
| SCHEMBL25386004 | 0.90 | AKT1 (0.72) | AKT1AKT2AKT3 | |
| SCHEMBL2190144 | 0.89 | AKT1 (0.77) | AKT1AKT2AKT3 | |
| SCHEMBL2174248 | 0.89 | AKT1 (0.93) | AKT1AKT2AKT3 | |
| SCHEMBL2190222 | 0.89 | AKT1 (0.80) | AKT1AKT2AKT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073371-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |
| WO-2024064026-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-03-28 | — | — | WO | disclosed |
| WO-2023168291-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2023-09-07 | — | — | WO | disclosed |
| EP-2519522-A2 | SUBSTITUTED IMIDAZOPYRIDINYL-AMINOPYRIDINE COMPOUNDS | ArQule, Inc. (US) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011082270-A2 | SUBSTITUTED IMIDAZOPYRIDINYL-AMINOPYRIDINE COMPOUNDS | ARQULE. INC. (US) | 2011-07-07 | — | — | WO | disclosed |