Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30951445 | 1.00 | TDP1 (0.41) | TDP1ALDH1A1PKM | |
| SCHEMBL23748091 | 0.88 | TDP1 (0.39) | TDP1 | |
| SCHEMBL30951365 | 0.88 | TDP1 (0.39) | TDP1 | |
| SCHEMBL10846450 | 0.82 | TDP1 (0.44) | TDP1ALDH1A1PKM | |
| SCHEMBL7832945 | 0.78 | TDP1 (0.41) | TDP1ALDH1A1PKM | |
| SCHEMBL30500471 | 0.78 | TDP1 (0.41) | TDP1ALDH1A1PKM | |
| SCHEMBL27772336 | 0.78 | TDP1 (0.41) | TDP1ALDH1A1PKM | |
| SCHEMBL27325471 | 0.77 | TDP1 (0.40) | TDP1 | |
| SCHEMBL30951321 | 0.76 | NPSR1 (0.46) | TDP1 | |
| SCHEMBL1268563 | 0.75 | TDP1 (0.39) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3863635-A1 | THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS | Terns, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |
| EP-3840755-A1 | THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS | Terns, Inc. (US) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020041741-A1 | THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS | Terns, Inc. (US) | 2020-02-27 | — | — | WO | disclosed |