Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.67 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Serine SCHEMBL1018119 | 1.00 | PTGS1 (0.67) | PTGS1SLC7A11SLC7A5ENPEPSLC1A1 | |
| Serine SCHEMBL27493874 | 1.00 | PTGS1 (0.67) | PTGS1SLC7A11SLC7A5ENPEPSLC1A1 | |
| Serine SCHEMBL15417923 | 0.93 | PTGS1 (0.57) | PTGS1SLC7A11SLC7A5ENPEPSLC1A1 | |
| Cysteine SCHEMBL1675940 | 0.91 | PTGS1 (0.80) | PTGS1SLC7A11SLC7A5ENPEPSLC1A1 | |
| Cysteine SCHEMBL523189 | 0.91 | PTGS1 (0.80) | PTGS1SLC7A11SLC7A5ENPEPSLC1A1 | |
| Cysteine SCHEMBL14485654 | 0.91 | PTGS1 (0.80) | PTGS1SLC7A11SLC7A5ENPEPSLC1A1 | |
| Cysteine SCHEMBL1675939 | 0.91 | PTGS1 (0.80) | PTGS1SLC7A11SLC7A5ENPEPSLC1A1 | |
| Serine SCHEMBL1162414 | 0.91 | PTGS1 (0.80) | PTGS1SLC7A11SLC7A5ENPEPSLC1A1 | |
| Serine SCHEMBL17113864 | 0.91 | PTGS1 (0.80) | PTGS1SLC7A11SLC7A5ENPEPSLC1A1 | |
| Serine SCHEMBL1162408 | 0.91 | PTGS1 (0.80) | PTGS1SLC7A11SLC7A5ENPEPSLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107753-A2 | TREATMENT OF ASCT2-DEPENDENT CANCERS | NEUPHARMA, INC (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024092274-A2 | ENDOCYTIC AGENTS | BIOVENTURES, LLC (US) | 2024-05-02 | — | — | WO | disclosed |
| CN-117230186-B | Application of glutamine transporter ASCT2 as target in preparation of medicines for treating Tfh-related autoimmune diseases | 中国医学科学院皮肤病医院(中国医学科学院皮肤病研究所) | 2024-01-26 | — | — | CN | disclosed |
| US-20230416199-A1 | INHIBITORS OF AMINO ACID TRANSPORT | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-12-28 | — | — | US | disclosed |
| US-20230416199-A1 | INHIBITORS OF AMINO ACID TRANSPORT | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-12-28 | — | — | US | disclosed |
| CN-117230186-A | Application of glutamine transporter ASCT2 as target in preparation of medicines for treating Tfh-related autoimmune diseases | 中国医学科学院皮肤病医院(中国医学科学院皮肤病研究所) | 2023-12-15 | — | — | CN | disclosed |
| WO-2022087630-A1 | INHIBITORS OF AMINO ACID TRANSPORT | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-04-28 | — | — | WO | disclosed |
| WO-2022087630-A1 | INHIBITORS OF AMINO ACID TRANSPORT | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-04-28 | — | — | WO | disclosed |
| US-20210379109-A1 | IMMUNOTHERAPY WITH METABOLIC ENZYME EXPRESSION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-12-09 | — | — | US | disclosed |
| WO-2020041662-A1 | IMMUNOTHERAPY WITH METABOLIC ENZYME EXPRESSION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2020-02-27 | — | — | WO | disclosed |
| CN-108366990-A | Synthetic sphingolipid molecules, drugs, methods of their synthesis and methods of treatment | 加利福尼亚大学董事会 | 2018-08-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416199-A1 | INHIBITORS OF AMINO ACID TRANSPORT | SLC1A5, SLC7A1, SLC7A5 | PTGS1 2331/4885SLC7A11 9/4885SLC7A5 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.