Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 5/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.55 |
| ▸ | FAAH | O00519 | 3/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GMNN | O75496 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL445573 | 1.00 | S1PR2 (0.55) | S1PR2S1PR1S1PR3S1PR4FAAH | |
| SCHEMBL10795834 | 1.00 | S1PR2 (0.55) | S1PR2S1PR1S1PR3S1PR4FAAH | |
| SCHEMBL21752772 | 1.00 | S1PR2 (0.55) | S1PR2S1PR1S1PR3S1PR4FAAH | |
| SCHEMBL5280575 | 1.00 | S1PR2 (0.55) | S1PR2S1PR1S1PR3S1PR4FAAH | |
| SCHEMBL21199830 | 1.00 | S1PR2 (0.55) | S1PR2S1PR1S1PR3S1PR4FAAH | |
| SCHEMBL21199828 | 1.00 | S1PR2 (0.55) | S1PR2S1PR1S1PR3S1PR4FAAH | |
| SCHEMBL23390575 | 1.00 | S1PR2 (0.55) | S1PR2S1PR1S1PR3S1PR4FAAH | |
| SCHEMBL21199406 | 1.00 | S1PR2 (0.55) | S1PR2S1PR1S1PR3S1PR4FAAH | |
| SCHEMBL21199407 | 1.00 | S1PR2 (0.55) | S1PR2S1PR1S1PR3S1PR4FAAH | |
| SCHEMBL506443 | 1.00 | S1PR2 (0.55) | S1PR2S1PR1S1PR3S1PR4FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041500-A1 | TREATMENT OF FLAVIVIRUS INFECTIONS IN HUMANS USING MUS MUSCULUS RESISTANT 2'-5' OLIGOADENYLATE SYNTHETASE 1B | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2020-02-27 | — | — | WO | disclosed |