Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23692353 | 0.91 | NTRK1 (0.51) | NTRK1 | |
| SCHEMBL23761803 | 0.91 | NTRK1 (0.51) | NTRK1 | |
| SCHEMBL21752815 | 0.90 | NTRK1 (0.54) | NTRK1 | |
| SCHEMBL29894575 | 0.89 | NTRK1 (0.46) | NTRK1 | |
| SCHEMBL21637234 | 0.89 | NTRK1 (0.46) | NTRK1 | |
| SCHEMBL21752908 | 0.86 | NTRK1 (0.38) | NTRK1 | |
| SCHEMBL30055958 | 0.86 | NTRK1 (0.42) | NTRK1 | |
| SCHEMBL21765947 | 0.86 | NTRK1 (0.42) | NTRK1 | |
| SCHEMBL21752912 | 0.86 | NTRK1 (0.42) | NTRK1 | |
| SCHEMBL21752828 | 0.85 | NTRK1 (0.55) | NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3840832-A1 | IMIDAZO[1,2-B]PYRIDAZINES AS TRK INHIBITORS | BenevolentAI Bio Limited (GB) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020039209-A1 | IMIDAZO[1,2-B]PYRIDAZINES AS TRK INHIBITORS | BENEVOLENTAI BIO LIMITED (GB) | 2020-02-27 | — | — | WO | disclosed |