Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 5/20 | 0.42 |
| ▸ | PPARA | Q07869 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2175381 | 1.00 | HDAC1 (0.46) | HDAC1HDAC6TDP1PPARGPPARA | |
| SCHEMBL1750768 | 0.88 | PPARA (0.51) | HDAC1HDAC6TDP1PPARGPPARA | |
| SCHEMBL1750767 | 0.88 | PPARA (0.51) | HDAC1HDAC6TDP1PPARGPPARA | |
| SCHEMBL7815559 | 0.87 | ESR1 (0.55) | TDP1PPARAKMT2AESR1ESR2 | |
| SCHEMBL3155465 | 0.85 | PPARA (0.54) | PPARGPPARAPPARD | |
| SCHEMBL3155456 | 0.85 | PPARA (0.54) | PPARGPPARAPPARD | |
| SCHEMBL2173501 | 0.82 | HDAC1 (0.43) | HDAC1HDAC6TDP1PPARGPPARA | |
| SCHEMBL2173508 | 0.82 | HDAC1 (0.43) | HDAC1HDAC6TDP1PPARGPPARA | |
| SCHEMBL15446290 | 0.80 | HDAC1 (0.49) | HDAC1HDAC6TDP1PPARGPPARA | |
| SCHEMBL2175262 | 0.80 | PSMB5 (0.48) | HDAC1HDAC6PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973063-B2 | Methods for activating PPAR gamma-type receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-07-05 | — | — | US | disclosed |
| CN-1950335-A | Novel biaromatic compounds which activate PPAR.gamma.-type receptors, their process of preparation and their use in cosmetic or pharmaceutical compositions | GALDERMA RES & DEV (FR) | 2007-04-18 | — | — | CN | disclosed |