Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3183657 | 0.94 | ACE (0.55) | ACESMN1; SMN2HPGDALDH1A1CHRM2 | |
| SCHEMBL6039762 | 0.94 | ACE (0.55) | ACESMN1; SMN2HPGDALDH1A1CHRM2 | |
| SCHEMBL6786426 | 0.94 | ACE (0.55) | ACESMN1; SMN2HPGDALDH1A1CHRM2 | |
| SCHEMBL3183667 | 0.94 | ACE (0.55) | ACESMN1; SMN2HPGDALDH1A1CHRM2 | |
| SCHEMBL474742 | 0.88 | ACE (0.60) | ACESMN1; SMN2ALDH1A1CHRM2CHRM4 | |
| SCHEMBL474618 | 0.88 | ACE (0.60) | ACESMN1; SMN2ALDH1A1CHRM2CHRM4 | |
| SCHEMBL5741058 | 0.87 | HPGD (0.63) | ACESMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL5740226 | 0.87 | SMN1; SMN2 (0.54) | ACESMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL5740374 | 0.87 | SMN1; SMN2 (0.63) | ACESMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL5741063 | 0.87 | HPGD (0.63) | ACESMN1; SMN2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519506-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011082077-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-07-07 | — | — | WO | disclosed |