⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19675745 | 0.82 | — | — | |
| SCHEMBL19497512 | 0.72 | — | — | |
| SCHEMBL22013965 | 0.64 | — | — | |
| SCHEMBL18688641 | 0.64 | — | — | |
| SCHEMBL4567301 | 0.64 | — | — | |
| SCHEMBL24013601 | 0.63 | — | — | |
| SCHEMBL23195787 | 0.62 | — | — | |
| SCHEMBL18359718 | 0.61 | — | — | |
| SCHEMBL23195840 | 0.60 | — | — | |
| SCHEMBL19881207 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041562-A1 | SUBSTITUTED IMIDAZOLES FOR THE INHIBITION OF TGF-BETA AND METHODS OF TREATMENT | CLAVIUS PHARMACEUTICALS, LLC (US) | 2020-02-27 | — | — | WO | disclosed |