Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 5/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.42 |
| ▸ | ATR | Q13535 | 13/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22449808 | 0.81 | CYP4F2 (0.36) | CYP4F2CYP4A11ATRRXRARXRB | |
| SCHEMBL1649419 | 0.75 | CYP4F2 (0.41) | CYP4F2CYP4A11ATRRXRARXRB | |
| SCHEMBL28916707 | 0.72 | CYP4F2 (0.42) | CYP4F2CYP4A11ATRRXRARXRB | |
| SCHEMBL22951244 | 0.71 | CYP4F2 (0.47) | CYP4F2CYP4A11ATRRXRARXRB | |
| SCHEMBL18748296 | 0.70 | — | — | |
| SCHEMBL21439377 | 0.69 | CYP4F2 (0.45) | CYP4F2CYP4A11ATR | |
| SCHEMBL12693554 | 0.69 | CYP4F2 (0.47) | CYP4F2CYP4A11ATRRXRARXRB | |
| SCHEMBL8004755 | 0.69 | CYP4F2 (0.53) | CYP4F2CYP4A11ATRRXRARXRB | |
| SCHEMBL22943517 | 0.68 | CYP4F2 (0.44) | CYP4F2CYP4A11ATRRXRARXRB | |
| SCHEMBL21437982 | 0.68 | CYP4F2 (0.49) | CYP4F2CYP4A11ATRRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3841101-B1 | METHOD FOR PREPARING 2-[(3R)-3-METHYLMORPHOLIN-4-YL]-4-[1-METHYL-1H-PYRAZOL-5-YL)-8-(1H-PYRAZOL-5-YL)-1,7-NAPHTHYRIDINE | BAYER AG (DE) | 2023-05-03 | — | — | EP | disclosed |
| WO-2020039025-A1 | METHOD FOR PREPARING 2-[(3R)-3-METHYLMORPHOLIN-4-YL]-4-[1-METHYL-1H-PYRAZOL-5-YL)-8-(1H-PYRAZOL-5-YL)-1,7-NAPHTHYRIDINE | BAYER AKTIENGESELLSCHAFT (DE) | 2020-02-27 | — | — | WO | disclosed |