Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5986706 | 0.85 | — | — | |
| SCHEMBL7205082 | 0.84 | EPHX2 (0.42) | EPHX2GBA1 | |
| SCHEMBL7211449 | 0.84 | EPHX2 (0.42) | EPHX2GBA1 | |
| SCHEMBL7209031 | 0.82 | EPHX2 (0.41) | EPHX2GBA1 | |
| SCHEMBL7207714 | 0.82 | EPHX2 (0.41) | EPHX2GBA1 | |
| SCHEMBL7210764 | 0.82 | EPHX2 (0.41) | EPHX2GBA1 | |
| SCHEMBL7207720 | 0.82 | EPHX2 (0.41) | EPHX2GBA1 | |
| SCHEMBL7210761 | 0.82 | EPHX2 (0.41) | EPHX2GBA1 | |
| SCHEMBL7209033 | 0.82 | EPHX2 (0.41) | EPHX2GBA1 | |
| SCHEMBL22754933 | 0.82 | EPHX2 (0.35) | EPHX2SMN1; SMN2GBA1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3215509-B1 | SUBSTITUTED PYRROLO[1,2-A]PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | LYSOSOMAL THERAPEUTICS INC (US) | 2020-02-26 | — | — | EP | disclosed |