Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25899542 | 0.91 | CRBN (0.41) | CRBNDDB1 | |
| SCHEMBL22733426 | 0.89 | CRBN (0.44) | CRBNDDB1 | |
| SCHEMBL25951897 | 0.88 | CRBN (0.40) | CRBNDDB1 | |
| SCHEMBL25900179 | 0.85 | CRBN (0.48) | CRBNDDB1 | |
| SCHEMBL24294674 | 0.85 | CRBN (0.45) | CRBNDDB1 | |
| SCHEMBL20323937 | 0.85 | CRBN (0.45) | CRBNDDB1 | |
| SCHEMBL25771919 | 0.83 | CRBN (0.46) | CRBNDDB1 | |
| SCHEMBL29307105 | 0.83 | CRBN (0.43) | CRBNDDB1 | |
| SCHEMBL22512216 | 0.82 | CRBN (0.57) | CRBNDDB1 | |
| SCHEMBL19559158 | 0.82 | CRBN (0.50) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3594211-B1 | ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF | CELGENE CORP (US) | 2023-10-25 | — | — | EP | disclosed |
| WO-2020038415-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN (SHANGHAI), INC. (CN) | 2020-02-27 | — | — | WO | disclosed |