Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19503629 | 0.89 | CRBN (0.72) | CRBN | |
| SCHEMBL19503639 | 0.86 | CRBN (0.69) | CRBN | |
| SCHEMBL22828023 | 0.86 | CRBN (0.69) | CRBN | |
| SCHEMBL20760056 | 0.86 | CRBN (0.72) | CRBN | |
| SCHEMBL29369888 | 0.85 | CRBN (0.67) | CRBN | |
| SCHEMBL27139685 | 0.85 | CRBN (0.67) | CRBN | |
| SCHEMBL31443676 | 0.85 | CRBN (1.00) | CRBN | |
| SCHEMBL22291530 | 0.85 | CRBN (0.67) | CRBN | |
| SCHEMBL31444247 | 0.85 | CRBN (1.00) | CRBN | |
| SCHEMBL20234563 | 0.84 | CRBN (0.66) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038415-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN (SHANGHAI), INC. (CN) | 2020-02-27 | — | — | WO | disclosed |