Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21350491 | 0.85 | CRBN (0.43) | CRBNDDB1 | |
| SCHEMBL4401471 | 0.85 | CRBN (0.51) | CRBNDDB1 | |
| SCHEMBL24267061 | 0.80 | CRBN (0.43) | CRBNDDB1 | |
| SCHEMBL22511860 | 0.76 | DDB1 (0.45) | CRBNDDB1 | |
| SCHEMBL25992807 | 0.76 | CRBN (0.40) | CRBNDDB1 | |
| SCHEMBL4387822 | 0.76 | CRBN (0.46) | CRBNDDB1 | |
| SCHEMBL5354731 | 0.76 | CRBN (0.53) | CRBNDDB1 | |
| SCHEMBL4397706 | 0.75 | CRBN (0.46) | CRBNDDB1 | |
| SCHEMBL4393720 | 0.75 | CRBN (0.49) | CRBNDDB1 | |
| SCHEMBL4394553 | 0.75 | CRBN (0.59) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038415-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN (SHANGHAI), INC. (CN) | 2020-02-27 | — | — | WO | disclosed |