Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 13/20 | 0.47 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19779461 | 0.79 | EGFR (0.59) | EGFRERBB2ERBB4 | |
| SCHEMBL18633118 | 0.78 | EGFR (0.53) | EGFRERBB2ERBB4 | |
| SCHEMBL18595973 | 0.77 | EGFR (0.50) | EGFRERBB2ERBB4 | |
| SCHEMBL21965724 | 0.77 | EGFR (0.63) | EGFRERBB2ERBB4 | |
| SCHEMBL18427554 | 0.77 | EGFR (0.63) | EGFRERBB2ERBB4 | |
| SCHEMBL18633119 | 0.77 | EGFR (0.53) | EGFRERBB2ERBB4 | |
| SCHEMBL18595837 | 0.76 | EGFR (0.51) | EGFRERBB2ERBB4 | |
| SCHEMBL18427475 | 0.76 | EGFR (0.49) | EGFRERBB2ERBB4 | |
| SCHEMBL18873071 | 0.75 | EGFR (0.48) | EGFRERBB2ERBB4 | |
| SCHEMBL21761308 | 0.75 | EGFR (0.40) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022186-B1 | QUINAZOLINE DERIVATIVES, COMPOSITIONS THEREOF, AND USE AS PHARMACEUTICALS | SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2020-02-26 | — | — | EP | disclosed |