SCHEMBL21761364

SCHEMBL21761364

CC(C)(c1ccc(O[SiH3])cc1)c1ccc(O[SiH3])cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.46
ESR1 P03372 4/20 0.46
TSHR P16473 3/20 0.46
ESR2 Q92731 3/20 0.46
CYP3A4 P08684 2/20 0.46
AR P10275 2/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
HTR6 P50406 1/20 0.46
ESRRG P62508 1/20 0.46
SLC6A3 Q01959 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ALDH1A1 P00352 5/20 0.42
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
MAPT P10636 3/20 0.42
TP53 P04637 2/20 0.42
HIF1A Q16665 2/20 0.42
CYP1A2 P05177 1/20 0.42
PPARG P37231 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3358243 0.84 MAPT (0.52) HPGDTSHRHSD17B10ALDH1A1MAPT
SCHEMBL17651618 0.78 MAPK1 (0.34) HPGDHSD17B10ALDH1A1MAPTNPC1
SCHEMBL9393171 0.78 NPC1 (0.33) HPGDALDH1A1MAPTNPC1RAB9A
SCHEMBL13283512 0.77 HPGD (0.39) HPGDESR1TSHRESR2CYP3A4
SCHEMBL3822059 0.76 CA12 (0.38) ESR1TSHRESR2CYP3A4ALDH1A1
SCHEMBL10112753 0.76 CA1 (0.61) HPGDESR1TSHRESR2CYP3A4
SCHEMBL83852 0.76 CA1 (0.61) HPGDESR1TSHRESR2CYP3A4
SCHEMBL25986528 0.76 CA1 (0.61) HPGDESR1TSHRESR2CYP3A4
SCHEMBL9815633 0.74 HPGD (0.46) HPGDESR1TSHRESR2CYP3A4
SCHEMBL20980178 0.74 HPGD (0.46) HPGDESR1TSHRESR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11820869-B2 Method for depolymerising oxygenated polymer materials by nucleophilic catalysis COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2023-11-21 US disclosed
US-11820869-B2 Method for depolymerising oxygenated polymer materials by nucleophilic catalysis COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2023-11-21 US disclosed
EP-3841160-B1 METHOD FOR DEPOLYMERISING OXYGENATED POLYMER MATERIALS BY NUCLEOPHILIC CATALYSIS COMMISSARIAT ENERGIE ATOMIQUE (FR) 2022-05-11 EP disclosed
US-20210238380-A1 METHOD FOR DEPOLYMERISING OXYGENATED POLYMER MATERIALS BY NUCLEOPHILIC CATALYSIS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2021-08-05 US disclosed
WO-2020038775-A1 METHOD FOR DEPOLYMERISING OXYGENATED POLYMER MATERIALS BY NUCLEOPHILIC CATALYSIS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2020-02-27 WO disclosed