Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.84 |
| ▸ | ERBB2 | P04626 | 10/20 | 0.84 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.64 |
| ▸ | JAK3 | P52333 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16398699 | 0.92 | EGFR (0.79) | EGFRERBB2ERBB4JAK3 | |
| SCHEMBL16398696 | 0.92 | EGFR (0.79) | EGFRERBB2ERBB4JAK3 | |
| SCHEMBL17538540 | 0.92 | EGFR (0.87) | EGFRERBB2 | |
| SCHEMBL16405547 | 0.92 | EGFR (0.83) | EGFRERBB2ERBB4JAK3 | |
| SCHEMBL17498519 | 0.92 | EGFR (0.83) | EGFRERBB2ERBB4JAK3 | |
| SCHEMBL17538533 | 0.92 | EGFR (0.87) | EGFRERBB2 | |
| SCHEMBL17538529 | 0.91 | EGFR (1.00) | EGFRERBB2ERBB4JAK3 | |
| SCHEMBL17538532 | 0.91 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL19027162 | 0.91 | EGFR (0.88) | EGFRERBB2 | |
| SCHEMBL17538534 | 0.91 | EGFR (1.00) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022186-B1 | QUINAZOLINE DERIVATIVES, COMPOSITIONS THEREOF, AND USE AS PHARMACEUTICALS | SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2020-02-26 | — | — | EP | disclosed |