Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 6/20 | 0.38 |
| ▸ | AKT1 | P31749 | 7/20 | 0.34 |
| ▸ | AKT2 | P31751 | 7/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23328260 | 0.86 | MEN1 (0.35) | FGFR1AKT1AKT2FGFR4PDGFRB | |
| SCHEMBL22396654 | 0.85 | FGFR1 (0.42) | FGFR1FGFR4SRC | |
| SCHEMBL21761868 | 0.84 | FGFR4 (0.36) | FGFR1AKT1AKT2KDM4EFGFR4 | |
| SCHEMBL23328708 | 0.78 | FGFR1 (0.50) | FGFR1AKT1AKT2FGFR4PDGFRB | |
| SCHEMBL16246197 | 0.74 | CCNT1 (0.34) | FGFR1KDM4EFGFR4PDE4BMAPT | |
| SCHEMBL16246372 | 0.74 | FGFR4 (0.42) | FGFR1KDM4EFGFR4PDE4BMAPT | |
| SCHEMBL30089813 | 0.74 | FGFR4 (0.42) | FGFR1KDM4EFGFR4PDE4BMAPT | |
| SCHEMBL21783949 | 0.73 | FGFR1 (0.47) | FGFR1FGFR4SRC | |
| SCHEMBL21783951 | 0.72 | MEN1 (0.36) | FGFR1FGFR4 | |
| SCHEMBL20943044 | 0.72 | FGFR1 (0.38) | FGFR1FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038458-A1 | CLASS OF FUSED RING TRIAZOLE COMPOUND, PREPARATION METHOD, AND USE | 如东凌达生物医药科技有限公司 | 2020-02-27 | — | — | WO | disclosed |