Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 16/20 | 0.66 |
| ▸ | FGFR4 | P22455 | 12/20 | 0.66 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.53 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21761971 | 0.92 | FGFR1 (0.78) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL21761780 | 0.90 | FGFR1 (0.54) | FGFR1FGFR4FGFR2FGFR3EGFR | |
| SCHEMBL21761887 | 0.89 | FGFR4 (0.55) | FGFR1FGFR4FGFR2FGFR3EGFR | |
| SCHEMBL21761896 | 0.89 | FGFR1 (0.55) | FGFR1FGFR4FGFR2FGFR3EGFR | |
| SCHEMBL21761897 | 0.85 | FGFR1 (0.68) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL21761847 | 0.85 | FGFR1 (0.67) | FGFR1FGFR4FGFR2FGFR3EGFR | |
| SCHEMBL21761898 | 0.85 | FGFR1 (0.65) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL21761878 | 0.84 | FGFR1 (0.66) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL21761902 | 0.84 | FGFR1 (0.66) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL30044812 | 0.84 | FGFR1 (0.65) | FGFR1FGFR4FGFR2FGFR3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038458-A1 | CLASS OF FUSED RING TRIAZOLE COMPOUND, PREPARATION METHOD, AND USE | 如东凌达生物医药科技有限公司 | 2020-02-27 | — | — | WO | disclosed |