SCHEMBL21761965

SCHEMBL21761965

C[C@@H](c1ccc2scnc2c1)N1CCc2ccccc2CC1

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OGA O60502 16/20 0.55
ALDH1A1 P00352 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PIK3CA P42336 1/20 0.38
MTOR P42345 1/20 0.38
CYP2D6 P10635 1/20 0.37
MC4R P32245 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21761983 1.00 OGA (0.55) OGAALDH1A1HSD17B10PIK3CAMTOR
SCHEMBL26608080 1.00 OGA (0.55) OGAALDH1A1HSD17B10PIK3CAMTOR
SCHEMBL21761961 1.00 OGA (0.55) OGAALDH1A1HSD17B10PIK3CAMTOR
SCHEMBL20792767 0.94 OGA (0.54) OGAALDH1A1
SCHEMBL26622373 0.88 OGA (0.52) OGAALDH1A1PIK3CAMTOR
SCHEMBL21761864 0.87 OGA (0.51) OGAPIK3CAMTOR
SCHEMBL21762216 0.87 OGA (0.53) OGAPIK3CAMTOR
SCHEMBL21761922 0.87 OGA (0.51) OGAPIK3CAMTOR
SCHEMBL21753251 0.87 OGA (0.53) OGAPIK3CAMTOR
SCHEMBL21761865 0.87 OGA (0.51) OGAPIK3CAMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795165-B2 Tetrahydro-benzoazepine glycosidase inhibitors ASCENEURON SA (CH) 2023-10-24 US disclosed
US-11795165-B2 Tetrahydro-benzoazepine glycosidase inhibitors ASCENEURON SA (CH) 2023-10-24 US disclosed
US-11795165-B2 Tetrahydro-benzoazepine glycosidase inhibitors ASCENEURON SA (CH) 2023-10-24 US disclosed
US-20220380358-A1 TETRAHYDRO-BENZOAZEPINE GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2022-12-01 US disclosed
WO-2020039028-A1 TETRAHYDRO-BENZOAZEPINE GLYCOSIDASE INHIBITORS ASCENEURON S. A. (CH) 2020-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220380358-A1 TETRAHYDRO-BENZOAZEPINE GLYCOSIDASE INHIBITORS BACE1, BACE2, BCHE OGA 380/4885ALDH1A1 708/4885HSD17B10 409/4885
US-11795165-B2 Tetrahydro-benzoazepine glycosidase inhibitors BACE1, BACE2, BCHE OGA 380/4885ALDH1A1 708/4885HSD17B10 409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.