Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | CASR | P41180 | 3/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16871235 | 1.00 | AOC3 (0.47) | AOC3L3MBTL1TAAR1CASRSLC22A1 | |
| SCHEMBL16871396 | 0.89 | CASR (0.48) | AOC3L3MBTL1TAAR1CASRSLC22A1 | |
| SCHEMBL16871059 | 0.89 | CASR (0.48) | AOC3L3MBTL1TAAR1CASRSLC22A1 | |
| SCHEMBL11618270 | 0.85 | AOC3 (0.51) | AOC3L3MBTL1TAAR1CASR | |
| SCHEMBL2318103 | 0.84 | AOC3 (0.47) | AOC3L3MBTL1TAAR1CASRSLC22A1 | |
| SCHEMBL15096064 | 0.84 | CASR (0.44) | AOC3L3MBTL1TAAR1CASRSLC22A1 | |
| SCHEMBL2359719 | 0.84 | AOC3 (0.47) | AOC3L3MBTL1TAAR1CASRSLC22A1 | |
| SCHEMBL15474083 | 0.84 | AOC3 (0.47) | AOC3L3MBTL1TAAR1CASRSLC22A1 | |
| SCHEMBL15121380 | 0.84 | AOC3 (0.53) | AOC3L3MBTL1TAAR1CASRSLC22A1 | |
| SCHEMBL18320847 | 0.83 | AOC3 (0.50) | AOC3L3MBTL1TAAR1CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150183727-A1 | METHOD FOR THE PREPARATION OF 1-ARYL-1-ALKYL-2-ALKYL-3-DIALKYLAMINOPROPANE COMPOUNDS | SIEGFRIED AG (CH) | 2015-07-02 | — | — | US | disclosed |
| WO-2011080756-A1 | PROCESS FOR THE PREPARATION OF 1-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVES | IND-SWIFT LABORATORIES LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183727-A1 | METHOD FOR THE PREPARATION OF 1-ARYL-1-ALKYL-2-ALKYL-3-DIALKYLAMINOPROPANE COMPOUNDS | CYP3A43, CYP1A2, CYP2C8 | AOC3 124/4885L3MBTL1 1979/4885TAAR1 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.