SCHEMBL21764494

SCHEMBL21764494

Clc1ccc2c3ccccc3c3ccccc3c3ccccc3c3ccccc3c2c1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.54
CYP2A6 P11509 2/20 0.48
KDM4E B2RXH2 1/20 0.47
PARP1 P09874 1/20 0.45
CYP1A2 P05177 1/20 0.43
HPRT1 P00492 3/20 0.41
TP53 P04637 1/20 0.41
PTGES O14684 2/20 0.41
JAK2 O60674 1/20 0.41
TBXAS1 P24557 1/20 0.41
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
TSHR P16473 1/20 0.40
SLC2A1 P11166 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9174497 1.00 AHR (0.54) AHRCYP2A6KDM4EPARP1CYP1A2
SCHEMBL19977161 1.00 AHR (0.54) AHRCYP2A6KDM4EPARP1CYP1A2
SCHEMBL25081281 0.92 AHR (0.48) AHRCYP2A6KDM4EPARP1CYP1A2
SCHEMBL21422585 0.92 AHR (0.48) AHRCYP2A6KDM4EPARP1CYP1A2
SCHEMBL30258139 0.92 AHR (0.48) AHRCYP2A6KDM4EPARP1CYP1A2
SCHEMBL30257398 0.92 AHR (0.48) AHRCYP2A6KDM4EPARP1CYP1A2
SCHEMBL25081953 0.90 AHR (0.47) AHRCYP2A6KDM4EPARP1CYP1A2
SCHEMBL30257816 0.90 AHR (0.47) AHRCYP2A6KDM4EPARP1CYP1A2
SCHEMBL25081282 0.87 AHR (0.48) AHRCYP2A6KDM4EPARP1CYP1A2
SCHEMBL25081971 0.87 AHR (0.48) AHRCYP2A6KDM4EPARP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3227269-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-02-26 EP disclosed