Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 10/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2176483 | 1.00 | PTGER1 (0.56) | PTGER1THRBNPC1RAB9ALMNA | |
| SCHEMBL2173616 | 0.93 | PTGER1 (0.55) | PTGER1THRBLMNAMEN1KMT2A | |
| SCHEMBL2173610 | 0.93 | PTGER1 (0.55) | PTGER1THRBLMNAMEN1KMT2A | |
| SCHEMBL2175487 | 0.93 | PTGER1 (0.59) | PTGER1THRBLMNAALDH1A1HPGD | |
| SCHEMBL2175483 | 0.93 | PTGER1 (0.59) | PTGER1THRBLMNAALDH1A1HPGD | |
| SCHEMBL13894309 | 0.92 | PTGER1 (0.53) | PTGER1THRBNPC1RAB9ALMNA | |
| SCHEMBL13894296 | 0.91 | PTGER1 (0.58) | PTGER1THRBNPC1RAB9ALMNA | |
| SCHEMBL2174925 | 0.90 | PTGER1 (0.53) | PTGER1THRBLMNAMEN1KMT2A | |
| SCHEMBL2174921 | 0.90 | PTGER1 (0.53) | PTGER1THRBLMNAMEN1KMT2A | |
| SCHEMBL12487341 | 0.89 | PTGER1 (0.64) | PTGER1THRBNPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973078-B2 | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2011-07-05 | — | — | US | claimed |