Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15714840 | 1.00 | IRAK4 (0.53) | IRAK4ALDH1A1MAPTALOX15P2RX3 | |
| SCHEMBL16884064 | 0.89 | IRAK4 (0.51) | IRAK4ALDH1A1MAPTALOX15KDM4E | |
| SCHEMBL16873155 | 0.89 | IRAK4 (0.51) | IRAK4ALDH1A1MAPTALOX15KDM4E | |
| SCHEMBL15688990 | 0.89 | IRAK4 (0.51) | IRAK4ALDH1A1MAPTALOX15KDM4E | |
| SCHEMBL30606147 | 0.89 | IRAK4 (0.43) | IRAK4MAPTKDM4E | |
| SCHEMBL29709761 | 0.87 | IRAK4 (0.53) | IRAK4ALDH1A1MAPTALOX15KDM4E | |
| SCHEMBL1521991 | 0.87 | IRAK4 (0.53) | IRAK4ALDH1A1MAPTALOX15KDM4E | |
| SCHEMBL31160381 | 0.87 | IRAK4 (0.45) | IRAK4ALDH1A1MAPTALOX15KDM4E | |
| SCHEMBL16872967 | 0.86 | IRAK4 (0.46) | IRAK4ALDH1A1MAPTALOX15KDM4E | |
| SCHEMBL16878927 | 0.84 | IRAK4 (0.49) | IRAK4ALDH1A1MAPTALOX15P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475270-B1 | HETEROARYL SUBSTITUTED AMINOPYRIDINE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2020-02-26 | — | — | EP | disclosed |