Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | BID | P55957 | 3/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.34 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | F7 | P08709 | 2/20 | 0.34 |
| ▸ | F3 | P13726 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21299300 | 0.90 | CYP3A4 (0.60) | CYP3A4CYP2D6CYP2C9LIPGTLR8 | |
| SCHEMBL5666344 | 0.88 | CYP3A4 (0.53) | CYP3A4CYP2D6CYP2C9LIPGKDM4E | |
| SCHEMBL5921320 | 0.85 | CYP3A4 (0.52) | CYP3A4CYP2D6CYP2C9LIPGBID | |
| SCHEMBL5920392 | 0.85 | CYP3A4 (0.52) | CYP3A4CYP2D6CYP2C9LIPGBID | |
| SCHEMBL5921445 | 0.84 | CYP3A4 (0.51) | CYP3A4CYP2D6CYP2C9LIPGPTGS2 | |
| SCHEMBL5920680 | 0.83 | CYP3A4 (0.50) | CYP3A4CYP2D6CYP2C9LIPGTHRA | |
| SCHEMBL5920073 | 0.83 | CYP3A4 (0.50) | CYP3A4CYP2D6CYP2C9LIPGTHRA | |
| SCHEMBL7644622 | 0.82 | CYP3A4 (0.60) | CYP3A4CYP2D6CYP2C9LIPGKDM4E | |
| SCHEMBL5677442 | 0.82 | CYP3A4 (0.49) | CYP3A4CYP2D6CYP2C9LIPGBID | |
| SCHEMBL48878 | 0.82 | CYP3A4 (0.59) | CYP3A4CYP2D6CYP2C9LIPGTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11028230-B1 | Method for condensation polymerization of hydroxyl-terminated polydiorganosiloxanes | DOW SILICONES CORPORATION (US) | 2021-06-08 | — | — | US | disclosed |
| US-20210163686-A1 | METHOD FOR CONDENSATION POLYMERIZATION OF HYDROXYL-TERMINATED POLYDIORGANOSILOXANES | DOW GLOBAL TECHNOLOGIES LLC | 2021-06-03 | — | — | US | disclosed |
| WO-2020040885-A1 | METHOD FOR CONDENSATION POLYMERIZATION OF HYDROXYL-TERMINATED POLYDIORGANOSILOXANES | DOW SILICONES CORPORATION (US) | 2020-02-27 | — | — | WO | disclosed |