Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLQ | O75417 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28347861 | 0.92 | GSK3B (0.45) | KMT2AALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL8552126 | 0.90 | POLQ (0.48) | KMT2APOLQMAPTLMNA | |
| SCHEMBL7501648 | 0.90 | GSK3B (0.47) | KMT2APOLQALDH1A1MAPTHPGD | |
| SCHEMBL2189058 | 0.89 | KMT2A (0.59) | KMT2APOLQALDH1A1POLBMEN1 | |
| Water SCHEMBL11223681 | 0.88 | KMT2A (0.39) | KMT2APOLQALDH1A1MAPTHPGD | |
| Water SCHEMBL11223686 | 0.88 | KMT2A (0.39) | KMT2APOLQALDH1A1MAPTHPGD | |
| SCHEMBL30520315 | 0.87 | GSK3B (0.53) | ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL11922926 | 0.85 | KMT2A (0.41) | KMT2AALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL3152935 | 0.84 | GSK3B (0.53) | KMT2AALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL1244024 | 0.84 | NOTUM (0.62) | KMT2AALDH1A1MAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |