Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.41 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765697 | 0.92 | NOTUM (0.52) | BLMNAMPTALDH1A1MEN1TSHR | |
| SCHEMBL4773392 | 0.83 | NOTUM (0.61) | BLMNAMPTMEN1KMT2ALMNA | |
| SCHEMBL15989340 | 0.79 | ESR1 (0.53) | NAMPTHSP90AA1 | |
| SCHEMBL21765682 | 0.77 | NAMPT (0.36) | NAMPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL21606912 | 0.77 | AOC3 (0.47) | NAMPTDPP8DPP9DPP7 | |
| SCHEMBL21606988 | 0.77 | AOC3 (0.47) | NAMPTTSHRKMT2ALMNASMN1; SMN2 | |
| SCHEMBL21606902 | 0.77 | AOC3 (0.47) | NAMPTDPP8DPP9DPP7 | |
| SCHEMBL23518496 | 0.77 | HDAC6 (0.41) | NAMPTNOTUMDPP8DPP9DPP7 | |
| SCHEMBL18170310 | 0.76 | — | — | |
| SCHEMBL14996180 | 0.74 | KMT2A (0.67) | ALDH1A1MEN1TSHRKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |