Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765943 | 1.00 | NTRK1 (0.44) | NTRK1USP30 | |
| SCHEMBL30334971 | 1.00 | NTRK1 (0.44) | NTRK1USP30 | |
| SCHEMBL23761653 | 1.00 | NTRK1 (0.44) | NTRK1USP30 | |
| SCHEMBL23761805 | 0.97 | NTRK1 (0.45) | NTRK1USP30 | |
| SCHEMBL23761822 | 0.95 | NTRK1 (0.43) | NTRK1 | |
| SCHEMBL23761654 | 0.92 | NTRK1 (0.41) | NTRK1USP30 | |
| SCHEMBL30921642 | 0.91 | NTRK1 (0.49) | NTRK1USP30 | |
| SCHEMBL23761659 | 0.91 | NTRK1 (0.49) | NTRK1USP30 | |
| SCHEMBL23692444 | 0.91 | NTRK1 (0.45) | NTRK1USP30 | |
| SCHEMBL21752908 | 0.91 | NTRK1 (0.38) | NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039209-A1 | IMIDAZO[1,2-B]PYRIDAZINES AS TRK INHIBITORS | BENEVOLENTAI BIO LIMITED (GB) | 2020-02-27 | — | — | WO | disclosed |