SCHEMBL21766322

SCHEMBL21766322

CCn1nc(C)c(F)c1C(=O)Nc1nc2cc(C(N)=O)cc3c2n1CC(C)(C)CN3CCOCc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21766386 0.90 STING1 (0.41) STING1
SCHEMBL21753398 0.88 STING1 (0.54) STING1
SCHEMBL21766389 0.87 STING1 (0.41) STING1
SCHEMBL21766314 0.87 STING1 (0.39) STING1
SCHEMBL21766318 0.83 STING1 (0.40) STING1
SCHEMBL21766316 0.83 STING1 (0.40) STING1
SCHEMBL21766145 0.82 STING1 (0.39) STING1
SCHEMBL21766388 0.81 STING1 (0.40) STING1
SCHEMBL21766298 0.81 STING1 (0.40) STING1
SCHEMBL21766144 0.81 STING1 (0.40) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3842437-A1 HIGH ACTIVITY STING PROTEIN AGONIST Adlai Nortye Biopharma Co., Ltd. (CN) 2021-06-30 EP disclosed
WO-2020038387-A1 HIGH ACTIVITY STING PROTEIN AGONIST 杭州阿诺生物医药科技有限公司 2020-02-27 WO disclosed