Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM3 | Q86V86 | 7/20 | 1.00 |
| ▸ | PIM1 | P11309 | 14/20 | 0.84 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2179303 | 0.95 | PIM3 (0.90) | PIM3PIM1PIM2 | |
| SCHEMBL12497473 | 0.91 | PIM1 (1.00) | PIM3PIM1PIM2 | |
| SCHEMBL12499196 | 0.86 | PIM1 (0.79) | PIM3PIM1PIM2 | |
| SCHEMBL2175660 | 0.86 | PIM1 (1.00) | PIM3PIM1PIM2 | |
| SCHEMBL14762404 | 0.85 | PIM1 (1.00) | PIM3PIM1PIM2 | |
| SCHEMBL14768474 | 0.85 | PIM1 (1.00) | PIM3PIM1PIM2 | |
| SCHEMBL14551433 | 0.84 | PIM3 (0.73) | PIM3PIM1PIM2 | |
| SCHEMBL2180029 | 0.84 | PIM1 (1.00) | PIM3PIM1PIM2 | |
| SCHEMBL2178486 | 0.84 | PIM3 (0.73) | PIM3PIM1PIM2 | |
| SCHEMBL2175820 | 0.84 | PIM3 (1.00) | PIM3PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682991-B2 | Tricyclic compounds for use as kinase inhibitors | FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III (ES) | 2017-06-20 | — | — | US | claimed |
| EP-2519526-B1 | TRICYCLIC COMPOUNDS FOR USE AS KINASE INHIBITORS | CT NAC INVESTIGACIONES ONCOLOGICAS CNIO (ES) | 2014-03-26 | — | — | EP | claimed |
| EP-2519560-B1 | COPOLYMERS WITH PERFLUOROPOLYETHER SEGMENT AND MULTIPLE AMINOOXALYLAMINO GROUPS | 3M INNOVATIVE PROPERTIES CO (US) | 2017-06-28 | — | — | EP | disclosed |
| US-9682991-B2 | Tricyclic compounds for use as kinase inhibitors | FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III (ES) | 2017-06-20 | — | — | US | disclosed |
| US-9682991-B2 | Tricyclic compounds for use as kinase inhibitors | FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III (ES) | 2017-06-20 | — | — | US | disclosed |
| US-9682991-B2 | Tricyclic compounds for use as kinase inhibitors | FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III (ES) | 2017-06-20 | — | — | US | disclosed |
| US-9279035-B2 | Copolymers with perfluoropolyether segment and multiple aminooxalylamino groups | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-03-08 | — | — | US | disclosed |
| US-20150057428-A1 | COPOLYMERS WITH PERFLUOROPOLYETHER SEGMENT AND MULTIPLE AMINOOXALYLAMINO GROUPS | 3M INNOVATIVE PROPERTIES CO (US) | 2015-02-26 | — | — | US | disclosed |
| US-8907046-B2 | Copolymers with perfluoropolyether segment and multiple aminooxalylamino groups | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-12-09 | — | — | US | disclosed |
| EP-2519526-B1 | TRICYCLIC COMPOUNDS FOR USE AS KINASE INHIBITORS | CT NAC INVESTIGACIONES ONCOLOGICAS CNIO (ES) | 2014-03-26 | — | — | EP | disclosed |
| EP-2519526-B1 | TRICYCLIC COMPOUNDS FOR USE AS KINASE INHIBITORS | CT NAC INVESTIGACIONES ONCOLOGICAS CNIO (ES) | 2014-03-26 | — | — | EP | disclosed |
| US-20130065881-A1 | Tricyclic Compounds for Use as Kinase Inhibitors | CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (ES) | 2013-03-14 | — | — | US | disclosed |
| US-20130065881-A1 | Tricyclic Compounds for Use as Kinase Inhibitors | CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (ES) | 2013-03-14 | — | — | US | disclosed |
| US-20130065881-A1 | Tricyclic Compounds for Use as Kinase Inhibitors | CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (ES) | 2013-03-14 | — | — | US | disclosed |
| EP-2519526-A1 | TRICYCLIC COMPOUNDS FOR USE AS KINASE INHIBITORS | Centro Nacional de Investigaciones Oncológicas (CNIO) (ES) | 2012-11-07 | — | — | EP | disclosed |
| EP-2519560-A1 | COPOLYMERS WITH PERFLUOROPOLYETHER SEGMENT AND MULTIPLE AMINOOXALYLAMINO GROUPS | 3M Innovative Properties Company (US) | 2012-11-07 | — | — | EP | disclosed |
| US-20120259088-A1 | COPOLYMERS WITH PERFLUOROPOLYETHER SEGMENT AND MULTIPLE AMINOOXALYLAMINO GROUPS | 3M INNOVATIVE PROPERTIES COMPANY | 2012-10-11 | — | — | US | disclosed |
| WO-2011080510-A1 | TRICYCLIC COMPOUNDS FOR USE AS KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2011-07-07 | — | — | WO | disclosed |
| WO-2011082046-A1 | COPOLYMERS WITH PERFLUORPOLYETHER SEGMENT AND MULTIPLE AMINOOXALYLAMINO GROUPS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-07-07 | — | — | WO | disclosed |
| WO-2011080510-A1 | TRICYCLIC COMPOUNDS FOR USE AS KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065881-A1 | Tricyclic Compounds for Use as Kinase Inhibitors | PIM1, PIM2, PIM3 | PIM3 3/4885PIM1 1/4885PIM2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.