Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 4/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18815809 | 0.80 | TNF (0.41) | TBXA2RTP53BRD4GPR6 | |
| SCHEMBL18815805 | 0.77 | GALR3 (0.46) | BRD4GPR6PTAFR | |
| SCHEMBL18148898 | 0.77 | MEN1 (0.45) | TP53MAPTGPR6 | |
| Hydrochloric Acid SCHEMBL18815821 | 0.77 | TBXA2R (0.41) | TBXA2RTP53MAPT | |
| SCHEMBL7832218 | 0.74 | ATM (0.43) | TP53MAPT | |
| SCHEMBL18280252 | 0.71 | TP53 (0.46) | TP53MAPT | |
| SCHEMBL18280253 | 0.71 | TNF (0.41) | TP53GPR6 | |
| SCHEMBL18918984 | 0.70 | MEN1 (0.42) | TBXA2RTP53MAPTBRD4GPR6 | |
| SCHEMBL13508622 | 0.70 | KCNH2 (0.56) | TBXA2RMAPT | |
| SCHEMBL15552361 | 0.69 | AAK1 (0.42) | TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080118-B1 | TETRAHYDROIMIDAZOPYRIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB Biopharma SRL (BE) | 2020-03-04 | — | — | EP | disclosed |