Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30106507 | 1.00 | CHRM1 (0.38) | CHRM1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL21769300 | 0.92 | DHODH (0.35) | MAPTMEN1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL23566921 | 0.92 | DHODH (0.35) | MAPTMEN1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL24292883 | 0.82 | CHRM1 (0.41) | CHRM1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL16109883 | 0.77 | MAPT (0.51) | MAPTMEN1KMT2ACYP1A2LMNA | |
| SCHEMBL16109884 | 0.77 | MAPT (0.51) | MAPTMEN1KMT2ACYP1A2LMNA | |
| SCHEMBL15333607 | 0.77 | MAPT (0.52) | MAPTMEN1KMT2ACYP1A2LMNA | |
| SCHEMBL15333608 | 0.77 | MAPT (0.52) | MAPTMEN1KMT2ACYP1A2LMNA | |
| SCHEMBL17230360 | 0.77 | MAPT (0.52) | MAPTMEN1KMT2ACYP1A2LMNA | |
| SCHEMBL23585003 | 0.76 | MAPT (0.45) | MAPTMEN1KMT2ACYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842425-A1 | NOVEL QUINOLINE DERIVATIVE INHIBITOR | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020038460-A1 | NOVEL QUINOLINE DERIVATIVE INHIBITOR | 南京药捷安康生物科技有限公司 | 2020-02-27 | — | — | WO | disclosed |